Characterization of Nanomaterials
In the research and development of nanomaterials, the NanoCoulter™ single-particle analyzer can accurately measure particle size distribution, particle concentration, and zeta potential. It is particularly suitable for the characterization of surface-modified particles, polydisperse systems, and irregular particles. Compared with traditional optical methods, NanoCoulter™ provides more accurate and higher resolution results, offering strong data support for the optimization of nanomaterial preparation, stability evaluation, and quality control.
Detection of Agglomeration in Magnetic Nanoparticles
After surface coating, the properties of magnetic beads change, causing them to move closer to each other and form aggregates. The degree of agglomeration significantly affects downstream application efficiency. Therefore, it is essential to characterize the agglomeration level of the magnetic beads.NanoCoulter™’s single-particle, high-resolution detection enables accurate characterization of the agglomeration status in magnetic bead samples. The test results show that coated magnetic beads exhibit significantly higher levels of agglomeration, which is in excellent agreement with electron microscopy data.
Dispersion Analysis of Latex Microspheres
After antibody coating, latex microspheres often exhibit agglomeration, which can compromise the stability of downstream experiments. Therefore, proper dispersion treatment is required.
NanoCoulter™ enables precise analysis of particle size and surface charge (zeta potential) of microspheres before and after coating. It provides clear and intuitive visualization of agglomeration behavior, offering reliable data support for optimizing the coating process and dispersion conditions.
Microsphere Surface Engineering Analysis
Carboxyl content refers to the molar amount of carboxyl groups (-COOH) per unit mass or per unit surface area of the microspheres. It reflects the surface density of carboxyl groups and is a key parameter for evaluating the reactivity and binding capacity of the microspheres.A higher carboxyl content indicates more available binding sites on the microsphere surface, thereby improving conjugation efficiency with other molecules. As the carboxyl content increases, the absolute value of the zeta potential also increases.
MLCC Nano BaTiO₃ Slurry Particle Size Analysis
NanoCoulter™ single-particle analyzer can be used for the study of dispersion and storage stability of BaTiO₃ slurries. It offers high data resolution and is highly sensitive in detecting particle size uniformity as well as the presence of a small number of large particles.
Characterization of Nano Abrasives
Nano abrasives exhibit clear advantages over traditional abrasives in terms of particle size, grinding efficiency, and precision. While conventional abrasives tend to produce scratches and heat buildup due to their larger particle size, nano abrasives deliver smoother, more precise, and highly efficient grinding results.
RPS Particle Size Analysis of Flake Alumina Abrasives
The average particle size measured by NanoCoulter™ is slightly smaller than the SEM results. This is because RPS measures the equivalent spherical diameter, which is independent of particle shape. In contrast, SEM typically captures the maximum cross-sectional dimension for irregularly shaped particles and is more difficult to analyze statistically. For irregular or complex particle systems, customers generally consider RPS data to be more representative and reproducible, making it the ideal choice for efficient and reliable particle analysis.
Lithium-ion Battery Material Particle Size Distribution and Zeta Potential Analysis
By combining visual analysis with measurements of particle size, concentration, and single-particle zeta potential, NanoCoulter™ enables in-depth study of the dispersibility and surface functional group characteristics of lithium iron phosphate (LiFePO₄) cathode materials. This approach is highly suitable for material research and development, quality control, and other key stages in lithium battery material production.
Titanium Dioxide Particle Size Analysis
Nano titanium dioxide (nano TiO₂) is a white, loose powder with strong UV-shielding capability, excellent dispersibility, and superior weather resistance. It is widely used in cosmetics, functional fibers, plastics, coatings, paints, and other fields as a UV shielding agent to protect against ultraviolet radiation. It can also be applied in high-end automotive topcoats, providing a color-shifting (angle-dependent) effect.
NanoCoulter™ single-particle analyzer delivers particle size distribution and mean particle size results that are highly consistent with SEM data. It effectively overcomes the limitations of traditional optical methods (lower accuracy and resolution) and electron microscopy (lower throughput).
Hydrogel Material Characterization
The light absorbance and refractive index of hydrogel materials can significantly affect optical detection methods. NanoCoulter™ is unaffected by the optical properties of the sample and can accurately measure particle size and concentration. DLS measured the particle size of the sample at approximately 150 nm, while Atomic Force Microscopy (AFM) measured it at approximately 70 nm. NanoCoulter™ results showed a particle size of 73 nm and a concentration of 1.57–1.77 × 10¹¹ particles/mL, which is highly consistent with the theoretical mass concentration calculated from the feed material.
