Characterization of Nanomaterials

Nanomaterials exhibit extraordinary properties—high strength, light weight, and exceptional chemical reactivity—making them invaluable in applications ranging from functional additives and coatings to catalyst supports and energy materials.

The Nanocoulter™ Single-Particle Analyzer enables high-resolution analysis of individual nanoparticles, providing key parameters such as size, concentration, and surface charge. With its unmatched sensitivity and accuracy, Nanocoulter™ reveals the true characteristics of nanomaterials, empowering innovation in research, formulation, and quality control.

Magnetic Nanoparticles

The uniformity of magnetic nanobeads is crucial due to their tendency to aggregates. NanoCoulter™ accurately measuring particle size and distribution, revealing that ultrasonic Method A offers the best dispersion.

Latex Nanospheres

NanoCoulter™ enables precise analysis of nanosphere size and zeta potential changes before and after antibody coating, effectively monitoring aggregation. Ultrasonication or other treatments can be used to address this issue.

Characterization of Nanosphere Surface Modifications

Carboxyl content typically refers to the number of moles of carboxyl groups (–COOH) per unit mass or surface area of microspheres. It reflects the surface density of carboxyl groups on nanospheres and serves as a key parameter for evaluating their reactivity and binding capacity. A higher carboxyl content indicates more available binding sites on the microsphere surface, thereby enhancing the efficiency of interaction with other molecules.

The scatter plots of particle size and zeta-potential of PS microspheres with different amount of carboxyl

Particle Size Characterization of Nano-BaTiO₃ Slurry

The NanoCoulter™ single-particle analyzer can be used to study the dispersibility and storage stability of BaTiO₃ slurry. It offers high data resolution and is sensitive in detecting particle size uniformity as well as small populations of oversized particles in the tail of the distribution.