A high cost-performance instrument for measuring particle size and concentration.

Particle size range: 50 - 400 nm
Ultra-wide concentration detection range: 1×106 - 3×1011 particles/mL

Unparalleled Detection Performance

Particle size measurement precision comparable to electron microscopy

The NanoCoulter™ measures the average particle size and size distribution of polystyrene standard microspheres and other polydisperse samples,producing results that are fully consistent with SEM data, offering exceptionally high accuracy and precision.

Corresponding sizing data of Nanocoulter™
Electron microscopy results of the same sample

Measure concentration with high accuracy and repeatability

Samples were diluted in a gradient, and the concentration detection data showed a good linear relationship, consistent with the theoretical concentration(R² > 0.99). With 10 repeated tests, the coefficient of variation (CV) was less than 5%.

10 Repeated Test of the 100 nm Standard Nanosphere
100 nm Standard Sample tested 10 times repeatedly

Latest Articles & News

AAVs are promising gene therapy vectors due to their small size and favorable safety profile. However, accurately characterizing these sub-50 nm particles remains a major technical challenge in the field.
A recent study employed the NanoCoulter particle analyzer, based on resistive pulse sensing (RPS) technology, to comprehensively evaluate five commonly used EV isolation methods, providing valuable insights for researchers.
In the fields of nanotechnology and materials science, particle size distribution (PSD) is a critical parameter that directly influences the performance and applicability of nanomaterials. Two of the most commonly used indicators to evaluate PSD are the Polydispersity Index (PDI) and the SPAN value. While often used interchangeably, these two metrics differ significantly in how they are calculated and interpreted. Understanding the distinction between PDI and SPAN is essential for accurate particle characterization.