A high cost-performance instrument for measuring particle size and concentration.

Particle size range: 50 - 300 nm
Ultra-wide concentration detection range: 1×107 - 3×1011 particles/mL

Unparalleled Detection Performance
Electron Microscopy- Comparable Particle Size Determination
NanoCoulter™ measures both the particle size and size distribution of polydisperse samples, delivering EM-consistent results with exceptional accuracy and precision.
Measure Concentration with High Accuracy and Repeatability
Samples were serially diluted, and the concentration detection data demonstrated a strong linear correlation with the theoretical concentration (R² > 0.999). Across 10 repeated measurements, the coefficient of variation (CV) was less than 5%.
Latest Articles & News
AAVs are promising gene therapy vectors due to their small size and favorable safety profile. However, accurately characterizing these sub-50 nm particles remains a major technical challenge in the field.
Recently, NanoCoulter™ has gained growing recognition in exosome research, with multiple studies validating its analytical strengths. Below are highlights from several key publications.
In the fields of nanotechnology and materials science, particle size distribution (PSD) is a critical parameter that directly influences the performance and applicability of nanomaterials. Two of the most commonly used indicators to evaluate PSD are the Polydispersity Index (PDI) and the SPAN value. While often used interchangeably, these two metrics differ significantly in how they are calculated and interpreted. Understanding the distinction between PDI and SPAN is essential for accurate particle characterization.